Vernier Software and Technology
Vernier Software & Technology

Limitations on Cell Size: Surface Area to Volume

Figure from experiment 2 from Biology with Vernier


In order for cells to survive, they must constantly exchange ions, gases, nutrients, and wastes with their environment. These exchanges take place at the cell’s surface. To perform this function efficiently, there must be an adequate ratio between the cell’s volume and its surface area. As a cell’s volume increases, its surface area increases, but at a decreased rate. If you continued to increase the cell’s volume, it would soon be unable to efficiently exchange materials and the cell would die. This is the reason that the kidney cell of an elephant is the same general size as a mouse kidney cell.

In this lab activity, you will use agar cubes, which have a high salt content, as cell models. You will investigate how increasing a cell’s surface area while maintaining an equal volume affects the rate of material exchange with the environment. When the agar cubes are placed in distilled water, they will begin to dissolve, releasing sodium and chloride ions. The solution’s conductivity, measured by a Conductivity Probe, is proportional to the ion concentration in the solution.


In this experiment, you will

  • Use agar cubes cut into various size blocks to simulate cells.
  • Use a Conductivity Probe to measure the quantity of ions in a solution.
  • Determine the relationship between the surface area and volume of a cell.

Sensors and Equipment

This experiment features the following Vernier sensors and equipment.

Option 1

Option 2

Additional Requirements

You may also need an interface and software for data collection. What do I need for data collection?

Standards Correlations

See all standards correlations for Biology with Vernier »

Biology with Vernier

See other experiments from the lab book.

1Energy in Food
2Limitations on Cell Size: Surface Area to Volume
3Acids and Bases
4Diffusion through Membranes
5Conducting Solutions
6AEnzyme Action: Testing Catalase Activity
6BEnzyme Action: Testing Catalase Activity
8The Effect of Alcohol on Biological Membranes
9Biological Membranes
11ACell Respiration (O2)
11BCell Respiration (CO2)
11CCell Respiration (Pressure)
11DCell Respiration (CO2 and O2)
12ARespiration of Sugars by Yeast
12BSugar Fermentation
13Population Dynamics
14Interdependence of Plants and Animals
15Biodiversity and Ecosystems
16AEffect of Temperature on Respiration
16BEffect of Temperature on Fermentation
17Aerobic Respiration
18Acid Rain
19Dissolved Oxygen in Water
20Watershed Testing
21Physical Profile of a Lake
23AEffect of Temperature on Cold-Blooded Organisms
23BEffect of Temperature on Cold-Blooded Organisms
24ALactase Action
24BLactase Action
25Primary Productivity
26Control of Human Respiration
27Heart Rate and Physical Fitness
28Monitoring EKG
29Ventilation and Heart Rate
30Oxygen Gas and Human Respiration
31APhotosynthesis and Respiration (O2)
31BPhotosynthesis and Respiration (CO2)
31CPhotosynthesis and Respiration (CO2 and O2)

Experiment 2 from Biology with Vernier Lab Book

<em>Biology with Vernier</em> book cover

Included in the Lab Book

Vernier lab books include word-processing files of the student instructions, essential teacher information, suggested answers, sample data and graphs, and more.

Buy the Book

Dev Reference: VST0038

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